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Table 4 Subjects achieving prespecified IOP outcomes by diagnosis and gender, n (%) (ITT population)

From: Predictors of additional intraocular pressure reduction in patients changed to latanoprost/timolol fixed combination

  

Diagnosis

Patients with:

All

N = 383

OAG

N = 208

OHT

N = 161

Both

N = 14

≥5% IOP reduction from baseline to week 12

339 (88.5)

182 (87.5)

145 (90.1)

12 (85.7)

≥15% IOP reduction from baseline to week 12

298 (77.8)

156 (75.0)

131 (81.4)

11 (78.6)

IOP <16 mmHg at week 12

128 (33.4)

76 (36.5)

49 (30.4)

3 (21.4)

IOP <18 mmHg at week 12

255 (66.6)

138 (66.3)

107 (66.5)

10 (71.4)

 

Gender

 
 

Male

N = 179

 

Female

N = 204

 

≥5% IOP reduction from baseline to week 12

160 (89.4)

 

179 (87.7)

 

≥15% IOP reduction from baseline to week 12

146 (81.6)

 

152 (74.5)

 

IOP <16 mmHg at week 12

64 (35.8)

 

64 (31.4)

 

IOP <18 mmHg at week 12

126 (70.4)

 

129 (63.2)

 
  1. Both = OAG and OHT; IOP = intraocular pressure; ITT = intent-to-treat population;
  2. OAG = open-angle glaucoma; OHT = ocular hypertension.