Skip to main content

Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Table 4 Mean (SD) change in best-corrected visual acuity (VA; logMAR*) from baseline by early disease definition.

From: Newly diagnosed exudative age-related macular degeneration treated with pegaptanib sodium monotherapy in US community-based practices: medical chart review study

  Met definition Did not meet definition  
Early disease definition n Mean change (SD) n Mean change (SD) p-value
Definition No.1      
   Baseline to second treatment visit 18 0.04 (0.33) 41 -0.06 (0.21) 0.1702
   Baseline to third treatment visit 18 0.08 (0.29) 41 -0.06 (0.20) 0.0283
   Baseline to fourth treatment visit 18 0.12 (0.35) 41 -0.04 (0.26) 0.0597
   Baseline to month 6 visit 18 0.16 (0.39) 41 0.03 (0.31) 0.1799
Definition No.2      
   Baseline to second treatment visit 35 -0.06 (0.18) 31 0.03 (0.32) 0.1627
   Baseline to third treatment visit 35 -0.09 (0.18) 31 0.03 (0.28) 0.0339
   Baseline to fourth treatment visit 35 -0.08 (0.22) 31 0.09 (0.34) 0.0155
   Baseline to month 6 visit 35 -0.05 (0.28) 31 0.13 (0.34) 0.0235
  1. * Negative logMAR changes indicate improvement; positive logMAR changes indicate declination.
  2. Early disease definition No.1: lesion size < 2 disk area, baseline VA study eye ≥ 20/80 Snellen, no scar or atrophy.
  3. Early disease definition No.2: occult and better VA at baseline in fellow eye (worse in study eye).
  4. LogMAR = logarithm of the minimum angle of resolution; SD = standard deviation.