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Table 5 Mean change from baseline* in horizontal and vertical cup/disc ratios by visit, PP population

From: Long-term effect of latanoprost/timolol fixed combination in patients with glaucoma or ocular hypertension: A prospective, observational, noninterventional study

Visit

n

Mean ± SD (95% CI)

Horizontal cup/disc ratio

Month 6

645

0.0003 ± 0.13117

  

(-0.0099, 0.0104)

Month 12

660

0.0039 ± 0.13286

  

(-0.0063, 0.0140)

Month 18

666

0.0092 ± 0.13860

  

(-0.0014, 0.0197)

Month 24

666

0.0041 ± 0.14078

  

(-0.0067, 0.0148)

Last visit

783

0.0079 ± 0.14645

  

(-0.0024, 0.0182)

Vertical cup/disc ratio

Month 6

600

0.0040 ± 0.12772

  

(-0.0062, 0.0142)

Month 12

604

0.0075 ± 0.13726

  

(-0.0035, 0.0184)

Month 18

613

0.0152 ± 0.14613

  

(0.0036, 0.0268)

Month 24

615

0.0088 ± 0.13534

  

(-0.0019, 0.0195)

Last visit

729

0.0127 ± 0.15155

  

(0.0017, 0.0237)

  1. CI = confidence interval; PP = per protocol; SD = standard deviation.
  2. *Month × - baseline. Last visit = last postbaseline visit at which the parameter was recorded