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Table 2 Summary of characteristics of the 18 prospective and cross sectional studies

From: Clinical risk factors for age-related macular degeneration: a systematic review and meta-analysis

STUDY NAME

LOCATION

DATE OF STUDY

POPULATION

NUMBER OF LATE AMD SUBJECTS

AGE RANGE

% MALE

METHOD OF FUNDUS CAPTURE

METHOD OF CLASSIFICATION

AREDS [64]

USA

1992-1998

4,519

776

60-80

NA

Retinal photo

WARMGS

Baltimore Eye Study*[91]

USA

1985-1988

4,396

48

40+

NA

Retinal photo

International AMD

Barbados Eye Study*[42]

Barbados

1988-1992

2,374

12

40-84

43

Retinal photo

Described in paper

Beaver Dam Eye Study[24–26, 39, 47, 57, 92]

USA

1988-1990

4,926

72

43-86

44

Retinal photo

WARMGS

Blue Mountains Eye Study*[24–26, 35, 43, 46]

Australia

1992-1994

3,654

65

49+

43

Retinal photo

WARMGS

Cardiovascular Health Study[40]

USA

1989-1990

5,201

35

65+

60

Retinal photo

WARMGS

Copenhagen City Study*[33, 49]

Denmark

1986-1988, 2000-2002

946

112

60-80

49

Retinal photo

Described in paper

European Study of Eye Disease (EUREYE)[12]

Europe

2000-2003

4,752

158

Aged 65+

45

Retinal photo

International AMD

Funagata Study[30]

Japan

2000-2002

3,676

8

35+

51

Retinal photo

WARMGS

Los Angeles Latino Eye Study (LALES) *[53, 54, 61]

USA

1997-2002

5,875

25

40+

42

Retinal photo

WARMGS

Multi-ethnic Study of Atherosclerosis (MESA)[41, 59]

USA

2002-2004

6,176

27

45-85

48

Retinal photo

WARMGS

NHANES III*[58]

USA

1998-1994

8,270

54

40+

47

Retinal photo

WARMGS

PHS[34, 44]

USA

1982-1989

22,071

64

40+

100

Retinal photo

WARMGS

Progression of Age-related Macular Degeneration Study (PARMDS)[45]

USA

1989-1998

261

NA

60+

NA

Retinal photo

Modification of the Age-Related Eye Disease Study Grading system

Pathologie Occulaires Liees a l'age (POLA) *[51, 52]

France

2002, 2006

2,183

41

60+

43

Retinal photo

Fundus photo

Proyecto VER*[93]

USA

1997-1999

2,780

15

50+

39

Retinal photo

WARMGS

Rotterdam Study*[25, 26, 36, 62, 94]

Netherlands

1990-1993

6,251

104

55+

40

Retinal photo

WARMGS

Singapore Malay Eye Study (SiMES)[28, 31]

Singapore

1992

3,280

23

40-80

52

Retinal photo

WARMGS

  1. WARMGS: Wisconsin Age-Related Maculopathy Grading System; * Studies included in the meta-analyses
  2. * From article referenced
  3. Note: Case control studies were not included in this table