Table 1 Baseline demographic and clinical characteristics, ITT population*
Baseline IOP | ||
|---|---|---|
Characteristic | 20 to <24 mmHg N = 252 | ≥ 24 mmHg N = 320 |
Age, years | ||
Mean ± SD | 59.9 ± 12.2 | 59.1 ± 11.8 |
Gender, male | 117 (46.4) | 174 (54.4) |
Diagnosis | ||
Ocular hypertension | 150 (59.5) | 161 (50.3) |
Open-angle glaucoma | 102 (40.5) | 159 (49.7) |
Open-angle glaucoma grade† | ||
Mild | 77 (75.5) | 96 (60.4) |
Moderate | 21 (20.6) | 43 (27.0) |
Severe | 4 (3.9) | 20 (12.6) |
Intraocular pressure | ||
Mean (SD) | 22.2 ± 0.9 | 26.7 ± 2.8 |
Family history of ocular | ||
hypertension or glaucoma | 85 (33.7) | 73 (22.8) |
Body mass index | ||
Mean (SD) | 25.0 ± 3.9 | 25.1 ± 3.9 |
Comorbidities‡ | ||
Diabetes | 17 (8.7) | 33 (13.3) |
Hypertension | 69 (35.2) | 77 (30.8) |
Sleep disorders | 39 (19.8) | 34 (13.7) |
Myopia | 78 (31.0) | 95 (29.7) |
<-12 diopters | 1 (1.3) | 3 (3.2) |
Between -6 and -12 diopters | 9 (11.5) | 13 (13.7) |
>-6 diopters | 68 (87.2) | 79 (83.2) |
Tobacco use within prior year§ | 55 (28.1) | 83 (33.3) |