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Table 1 Baseline demographic characteristics and medical history*

From: A multicenter, retrospective chart review study comparing index therapy change rates in open-angle glaucoma or ocular hypertension patients newly treated with latanoprost or travoprost-Z monotherapy

 

Latanoprost

N = 632

Travoprost-Z

N = 268

Age, years

  

   Mean ± SD

66.7 ± 12.8

66.9 ± 11.1

   Median (range)

67.0 (32, 97)

66.5 (42, 96)

Gender

  

   Male

284 (45.0)

126 (47.6)

   Female

347 (55.0)

139 (52.5)

Diagnosis

  

   Primary open-angle glaucoma

499 (80.0)

214 (79.9)

   Ocular hypertension

119 (19.3)

52 (19.5)

Family history of glaucoma

  

   Yes

131 (20.7)

65 (24.3)

   No

501 (79.3)

203 (75.8)

Systemic comorbidities †

  

   Hypertension‡

322 (51.0)

159 (59.3)

   Lipid disorder

170 (26.9)

60 (22.4)

   Diabetes‡

108 (17.1)

65 (24.3)

   Thyroid disease

76 (12.0)

24 (9.0)

   Allergic rhinitis

50 (7.9)

17 (6.3)

   Asthma

40 (6.3)

19 (7.1)

   Depression

39 (6.2)

12 (4.5)

   Other

310 (49.1)

121 (45.2)

Coexisting ocular conditions †

  

   Cataract surgery

173 (27.4)

80 (29.9)

   Dry eye

83 (13.1)

27 (10.1)

   Macular degeneration

42 (6.7)

13 (4.9)

   Diabetic retinopathy

17 (2.7)

9 (3.4)

   Seasonal allergic conjunctivitis

7 (1.1)

6 (2.2)

   Other

319 (50.5)

154 (57.5)

Intraocular pressure§

  

   Right eye

  

   Mean ± SD

22.9 ± 6.2

23.1 ± 6.7

   Median

22

22

   Left eye

  

   Mean ± SD

22.4 ± 5.4

22.5 ± 5.5

   Median

22

22

  1. SD = standard deviation.
  2. *N (%) unless otherwise indicated.
  3. †Reported by ≥2% of patients in either cohort.
  4. ‡p < 0.05.
  5. §Latanoprost, N = 629; travoprost-X, N = 267.