| Within 6 months | Across full study period | ||
---|---|---|---|---|
 | Latanoprost N = 134 | Travoprost-Z N = 77 | Latanoprost N = 218 | Travoprost-Z N = 121 |
Type of change | Â | Â | Â | Â |
   Add-on | 36 (26.9) | 26 (33.8) | 62 (28.4) | 40 (33.1) |
   Switch | 65 (48.5) | 36 (46.8) | 102 (46.8) | 50 (41.3) |
   Discontinuation | 14 (10.5) | 5 (6.5) | 23 (10.6) | 13 (10.7) |
   Surgery/procedure | 19 (14.2) | 10 (13.0) | 31 (14.2) | 18 (14.9) |
Reason for change* | Â | Â | Â | Â |
   IOP not controlled | 83 (61.9) | 50 (64.9) | 119 (54.6) | 76 (62.8) |
   Adverse events | 16 (11.9) | 16 (20.8) | 24 (11.0) | 18 (14.9) |
   Physician preference | 11 (8.2) | 4 (5.2) | 21 (9.6) | 9 (7.4) |
   Non-compliance | 8 (6.0) | 2 (2.6) | 11 (5.0) | 6 (5.0) |
   Cost | 9 (6.7) | 3 (3.9) | 19 (8.7) | 4 (3.3) |
   Patient request | 5 (3.7) | 2 (2.6) | 10 (4.6) | 4 (3.3) |
   Ocular nerve head |  |  |  |  |
changes | 1 (0.7) | 0 | 6 (2.8) | 1 (0.8) |
   Other | 11 (8.2) | 3 (3.9) | 25 (11.5) | 5 (4.1) |