Cholesterol-enriched diet caused retinal morphological changes. A. Confocal microscopy showed an increase in immunoreactivity of vitronectin antibody (green) in the retinas of rabbits fed with cholesterol-enriched diet compared to rabbits fed with normal chow. B. Drusen like debris were detected under the retinal pigment epithelium (arrow) of cholesterol-fed rabbits. GCL-Ganglion Cell Layer; INL-Inner Nuclear Layer; ONL: Outer Nuclear Layer; PR-Photoreceptors; RPE-Retinal Pigment Epithelium. Bar = 20 μm.