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Table 1 Total cholesterol and oxysterol levels in control (n = 3) and cholesterol-fed rabbit retina (n = 3)

From: Cholesterol-enriched diet causes age-related macular degeneration-like pathology in rabbit retina

  Control retina Cholesterol-fed retina
Total cholesterol
mg/g tissue
0.1024 ± 0.028 0.8427 ± 0.002 ***
4β-hydroxycholesterol
ng/g tissue
2491 ± 236 9046 ± 1015**
7α-hydroxycholesterol
ng/g tissue
344.1 ± 49.51 14378 ± 1504 **
22-hydroxycholesterol
ng/g tissue
7.893 ± 1.59 105.6 ± 24.71 *
24-hydroxycholesterol
ng/g tissue
405.3 ± 173.9 1815.32 ± 313.5 *
25-hydroxycholesterol
ng/g tissue
24.39 ± 0.20 835.5 ± 29.77***
27-hydroxycholesterol
ng/g tissue
29.38 ± 8.4 697.2 ± 161.4 *
  1. Values are expressed as mean ± SEM. * p < 0.05; ** p < 0.01; *** p < 0.001 vs control.