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Table 1 Total cholesterol and oxysterol levels in control (n = 3) and cholesterol-fed rabbit retina (n = 3)

From: Cholesterol-enriched diet causes age-related macular degeneration-like pathology in rabbit retina

 

Control retina

Cholesterol-fed retina

Total cholesterol

mg/g tissue

0.1024 ± 0.028

0.8427 ± 0.002 ***

4β-hydroxycholesterol

ng/g tissue

2491 ± 236

9046 ± 1015**

7α-hydroxycholesterol

ng/g tissue

344.1 ± 49.51

14378 ± 1504 **

22-hydroxycholesterol

ng/g tissue

7.893 ± 1.59

105.6 ± 24.71 *

24-hydroxycholesterol

ng/g tissue

405.3 ± 173.9

1815.32 ± 313.5 *

25-hydroxycholesterol

ng/g tissue

24.39 ± 0.20

835.5 ± 29.77***

27-hydroxycholesterol

ng/g tissue

29.38 ± 8.4

697.2 ± 161.4 *

  1. Values are expressed as mean ± SEM. * p < 0.05; ** p < 0.01; *** p < 0.001 vs control.