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Table 2 Incidence of AMI in subjects with DME and age/gender matched diabetes controls*, 1 July 2002 to 31 December 2005

From: Hospitalized cardiovascular events in patients with diabetic macular edema

    DME Subjects    Diabetes Controls
Overall n Person-years AMI events rate/1000 PY 95% CI n Person-years AMI events rate/1000 PY 95% CI
All subjects 3519 4778.5 94 19.7 15.7 - 23.6 10557 13981.5 96 6.9 5.5 - 8.2
Females 1645 2220.9 38 17.1 11.7 - 22.5 4935 6502.4 40 6.2 4.3 - 8.1
Males 1874 2557.6 56 21.9 16.2 - 27.5 5622 7479.1 56 7.5 5.5 - 9.4
    DME Subjects    Diabetes Controls
Age (years) n Person-years AMI events rate/1000 PY 95% CI n Person-years AMI events rate/1000 PY 95% CI
18-29 49 58.5 0 0.0 0.0 - 0.0 157 178.5 0 0.0 0.0 - 0.0
30-39 217 280.9 2 7.1 0.0 - 16.9 591 772.9 3 3.9 0.0 - 8.3
40-49 517 717.6 9 12.5 4.4 - 20.7 1522 1969.7 4 2.0 0.0 - 4.0
50-59 1144 1531.4 28 18.3 11.6 - 25.0 3271 4293.2 17 4.0 2.1 - 5.8
60-69 937 1245.5 28 22.5 14.3 - 30.7 2971 3777.9 31 8.2 5.3 - 11.1
70-79 516 745.0 19 25.5 14.2 - 36.8 1521 2229.4 28 12.6 8.0 - 17.2
80-89 139 199.6 8 40.1 13.1 - 67.0 524 759.9 13 17.1 7.9 - 26.3
  1. *Diabetes controls - diabetes subjects without ophthalmic manifestations, retinal disorders, or vitreous hemorrhage.
  2. DME = diabetic macular edema; AMI = acute myocardial infarction; CVA = cerebrovascular accident; PY = person-years;
  3. CI = confidence interval.