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Table 5 Multivariate regression analysis on the association between total DES symptom score and VFQ-25 composite score, ocular pain subscale score, as well as mental health subscale score

From: Impact of Dry Eye Syndrome on Vision-Related Quality of Life in a Non-Clinic-Based General Population

   VFQ-25 composite score ocular pain subscale score mental health subscale score
β P value β P value β P value
Total DES symptom score Model 1 −0.501 <0.001 −0.836 0.001 −0.903 <0.001
  Model 2 −0.444 0.003 −0.842 0.001 −0.824 0.002
  Model 3 −0.448 0.003 −0.867 <0.001 −0.819 0.002
  Model 4 −0.428 0.008 −0.898 0.001 −0.811 0.003
  1. Values of β are standardized regression coefficients:
  2. Model 1, crude.
  3. Model 2, after the adjustment for age, gender, educational level and occupation.
  4. Model 3, after further adjustment for BCVA of the eye with more severe DES, BCVA of the eye with less severe DES or without DES, use of computer, and use of air conditioner.
  5. Model 4, after further adjustment for TBUT, ST and FFS.
  6. None of the clinical variables adjusted in model 2 to 4 met the 0.0500 significance level for entry into the final model.