| Pegaptanib sodium 0.3 mg | Sham | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Number of Subjects | With Diabetes | Without Diabetes | With Diabetes | |||||||||
 | (N = 165) | (N = 1421) | (N = 26) | |||||||||
Preferred Term 2 | n | (%) | Sev | LT | n | (%) | Sev | LT | n | (%) | Sev | Lt |
Acute myocardial infarction | 0 | 0 | 0 | 0 | 1 | (0.1) | 0 | 0 | 1 | (3.8) | 0 | 1 |
Angina pectoris | 1 | (0.6) | 1 | 0 | 8 | (0.6) | 2 | 1 | 1 | (3.8) | 0 | 0 |
Angina unstable | 0 | 0 | 0 | 0 | 4 | (0.3) | 2 | 0 | 0 | 0 | 0 | 0 |
Cardiac arrest | 0 | 0 | 0 | 0 | 2 | (0.1) | 0 | 2 | 0 | 0 | 0 | 0 |
Cardiac failure congestive | 0 | 0 | 0 | 0 | 5 | (0.4) | 1 | 2 | 1 | (3.8) | 1 | 0 |
Cerebral hemorrhage | 0 | 0 | 0 | 0 | 1 | (0.1) | 0 | 1 | 0 | 0 | 0 | 0 |
Cerebrovascular accident | 3 | (1.8) | 3 | 0 | 9 | (0.6) | 5 | 1 | 0 | 0 | 0 | 0 |
Coronary artery atherosclerosis | 2 | (1.2) | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Coronary artery disease NOS | 1 | (0.6) | 0 | 0 | 9 | (0.6) | 3 | 0 | 0 | 0 | 0 | 0 |
Coronary artery occlusion | 0 | 0 | 0 | 0 | 1 | (0.1) | 1 | 0 | 0 | 0 | 0 | 0 |
Myocardial infarction | 2 | (1.2) | 1 | 0 | 10 | (0.7) | 7 | 2 | 0 | 0 | 0 | 0 |
Pulmonary embolism | 1 | (0.6) | 1 | 0 | 7 | (0.5) | 4 | 1 | 0 | 0 | 0 | 0 |
Retroperitoneal hemorrhage | 0 | 0 | 0 | 0 | 1 | (0.1) | 1 | 0 | 1 | (0.1) | 1 | 0 |
Thrombosis | 1 | (0.6) | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Transient ischemic attack | 1 | (0.6) | 0 | 0 | 8 | (0.6) | 2 | 0 | 0 | 0 | 0 | 0 |
Silent myocardial infarction | 1 | (0.6) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ischemia NOS | 0 | 0 | 0 | 0 | 1 | (0.1) | 0 | 0 | 0 | 0 | 0 | 0 |
Deep vein thrombosis | 0 | 0 | 0 | 0 | 4 | (0.3) | 1 | 0 | 0 | 0 | 0 | 0 |