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Figure 1 | BMC Ophthalmology

Figure 1

From: Increased expression of oxyproteins in the optic nerve head of an in vivo model of optic nerve ischemia

Figure 1

Results of OxyBlot protein detection (A) and relative densitometric values of oxyprotein expression in the optic nerve head (B, C). Blotting was semi-quantified using densitometry. To compare the results of OxyBlot protein oxidation detection, relative densitometric values of treated groups were compared to control groups. Endothelin-1 (0.1 μg/day) was delivered to the perineural region of the anterior optic nerve by osmotically-driven minipumps for two (II), four (III), and eight weeks (IV). As a control, balanced salt solution was delivered for two (Ia) and eight weeks (Ib). There was a significant increase in the expression of oxyprotein after two weeks of endothelin-1 administration (p < 0.001, Mann Whitney U test). However, there was no difference between the two groups at eight weeks.

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