Table 1 Summary of the participants stratified by AMD phenotype
tAMD (n = 24) | PCV (n = 30) | Total (n = 54) | P value | |
|---|---|---|---|---|
Eye (right eye%) | 6 (25%) | 13 (43%) | 19 (35%) | 0.26✝ |
Gender (males%) | 18 (75%) | 21 (70%) | 39 (72%) | 0.92✝ |
Age, Mean (±SD) (years) | 73.2 (±8.5) | 76.0 (±7.6) | 74.7 (±8.1) | 0.21* |
Baseline Vision LogMAR (±SD) | 0.60 (±0.28) | 0.47 (±0.26) | 0.53 (±0.28) | 0.09* |
Baseline macular thickness (±SD) (μm) | 392 (±141) | 352 (±119) | 369 (±129) | 0.27* |
Baseline GLD (±SD) (μm) | 3610 (±962) | 4650 (±1665) | 4188 (±1480) | <0.01* |
BMI (±SD) | 22.6 (±4.0) | 22.1 (±2.8) | 22.4 (±3.4) | 0.62* |
Present or ever-smoking | 17 (71%) | 20 (67%) | 37 (69%) | 0.97✝ |
Hypertension | 11 (46%) | 13 (43%) | 24 (44%) | 0.92✝ |
Diabetic mellitus | 5 (21%) | 5 (17%) | 10 (19%) | 0.97✝ |
Previous PDT therapy | 0.40✝ | |||
0 | 16 (67%) | 18 (60%) | 34 (63%) | |
1 | 5 (21%) | 4 (13%) | 9 (17%) | |
2≦ | 3 (12%) | 8 (27%) | 11 (20%) | |
Subretinal hemorrhage (>1DA) | 4 (17%) | 8 (27%) | 12 (22%) | 0.58✝ |
Serous retinal detachment | 18 (75%) | 26 (87%) | 44 (81%) | 0.46✝ |
Macular edema | 11 (46%) | 12 (40%) | 23 (43%) | 0.88✝ |
Retinal pigmented epithelium detachment | 21 (88%) | 30 (100%) | 51 (94%) | 0.16✝ |
Subretinal fibrosis | 7 (29%) | 4 (13%) | 11 (20%) | 0.27✝ |