Skip to main content

Table 2 Comparison of the clinical characteristics between Group 1 (cases in which transparency was restored, n = 37) and Group 2 (cases in which transparency was not restored, n = 21)

From: Prognostic factors for corneal graft recovery after severe corneal graft rejection following penetrating keratoplasty

 

Group 1

Group 2

OR

P-value

 

mean ± SD

mean ± SD

(95% CI)

 
 

n (%)

n (%)

  

Age (years)

59.4 ± 15.5

68.3 ± 12.5

0.95 (0.91–1.00)

0.037

Sex

 Male

23 (62.2)

10 (47.6)

1.81 (0.61–5.34)

0.28

 Female

14 (37.8)

11 (52.4)

1.00

 

Diagnosis before PKP

 Bullous keratopathy

13 (35.1)

8 (38.1)

0.88 (0.29–2.67)

0.82

 Regraft

8 (21.6)

6 (28.6)

0.69 (0.20–2.36)

0.55

 Corneal scar

9 (24.3)

4 (19.0)

1.37 (0.36–5.13)

0.64

 Corneal dystrophy

3 (8.1)

1 (4.8)

1.76 (0.17–18.13)

0.63

 Keratoconus

3 (8.1)

0 (0.0)

1.00

 Corneal ulcer

1 (2.7)

2 (9.5)

0.26 (0.02–3.10)

0.29

Type of surgery

 PKP

27 (73.0)

16 (76.2)

0.84 (0.24–2.91)

0.79

 PKP + ECCE + IOL

9 (24.3)

4 (19.0)

1.37 (0.36–5.13)

0.64

 PKP + IOL suture

1 (2.7)

1 (4.8)

0.56 (0.03–9.37)

0.68

history of glaucoma

8 (21.6)

9 (42.9)

0.37 (0.11-1.18)

0.093

Previous episodes of rejection

4 (10.8)

4 (19.0)

0.51 (0.11–2.32)

0.38

ECD before rejection

1669 ± 747

806 ± 455

1.002 (1.001–1.004)

0.013

Interval between PKP and rejection (months)

33.3 ± 40.0

28.2 ± 30.7

1.00 (0.99–1.02)

0.61

Interval between rejection and treatment with systemic steroids (days)

6.2 ± 5.6

14.5 ± 12.8

0.88 (0.80–0.97)

0.0093

Systemic steroid

 Dexamethasone phosphate

29 (78.4)

18 (85.7)

0.60 (0.14–2.58)

0.50

 Methylprednisolone

8 (21.6)

3 (14.3)

1.66 (0.39–7.07)

 
  1. ECCE, extracapsular cataract extraction; ECD, endothelial cell density; IOL, intraocular lens; PKP, penetrating keratoplasty; SD, standard deviation.