Table 3 Levels of total free (proform/active), active matrix metalloproteinases and tissue inhibitor metalloproteinases in aqueous humor

MMP2

7.13 ± 1.5 (5.3-10.2)

23.7 ±10.5 (7.16-44) (p < 0.001)*

15.8 ± 9.8 (6.1-29.3) (p < 0.001)*

23.4 ±17.3 (7.1-56.7) (p < 0.001)*

MMP3

3.11 ±0.8 (1.6-4.5)

7.5 ±15.8 (1.3-61) (p = 0.07)

6.8 ± 11.7 (1.3-44.,2) (p = 0.11)

9.8 ± 16.8 (1.5-72) (p < 0.001)*

MMP9

0.45 ± 0.25 (0.2-0.97)

0.7 ± 0.6 (0.2-2.1) (p = 0.08)

0.6 ± 0.33 (0.2-1.3) (p = 0.2)

0.6 ± 0.35 (0.17-1.5) (p = 0.2)

TIMP1

16.3 ± 6.1 (9.3-33.5)

33.6 ± 19.3 (11–75) (p < 0.001)*

31.2 ± 14.5 (12–58.5) (p < 0.001)*

37 ± 15 (15–60.3) (p < 0.001)*

TIMP2

3.7 ± 1.1 (2–5.7)

6.5 ± 3.1 ( 2.1-13.2) (p < 0.001)*

5.3 ± 2.1 (2.4-8.9) (p < 0.001)*

6.3 ± 3.1 (2.3-12.2) (p < 0.001)*

TIMP4

0.48 ± 0.25 (0.22-0.98)

0.95 ± 0.49 (0.24-1.76) (p < 0.001)*

0.48 ± 0.2 (0.13-0.76) (p = 0.93)

1.28 ± 1.38 (0.4-5.9) (p < 0.001)*

Active MMP2

0.21 ± 0.01 (0.2-0.24)

0.27 ± 0.06 (0.2-0.42) (p < 0.001)*

0.24 ± 0.03 (0.19-0.3) (p < 0.003)*

0.25 ± 0.04 (0.19-0.33) (p < 0.001)*

Active MMP3

0.29 ± 0.01 (0.26-0.3)

0.32 ± 0.02 (0.28-0.37) (p < 0.001)*

0.32 ± 0.01 (0.3-0.35) (p < 0.001)*

0.32 ± 0.2 (0.29-0.35) (p < 0.001)*

Act/tot. MMP2

0.008 ± 0,00086

0.006 ±0,00279 (p = 0.03)

0.005 ±0,00234 (p = 0.004)*

0.005 ± 0,00299 (p = 0.008)*

Act/tot. MMP3

0.008 ± 0,00183

0.008 ± 0,00061 (p = 0.93)

0.007 ± 0,0023 (p = 0.1)

0.008 ± 0,00072 (p = 0.93)