Table 1 Demographic data of patients undergoing optical coherence tomography
LHON patients (N = 52) | Normal (N = 14) | |||||
|---|---|---|---|---|---|---|
≤3 months | 3–6 months | 6–9 months | 9–12 months | >12 months | ||
Group | 1st | 2nd | 3rd | 4th | 5th | 6th |
Eyes | 10 | 11 | 10 | 9 | 12 | 14 |
Age | 18.40 ± 7.81 | 20.27 ± 6.31 | 22.90 ± 8.66 | 14.78 ± 5.19 | 23.08 ± 6.20 | 28.29 ± 14.64 |
Age of onset (years) | 18.00 ± 8.17 | 20.09 ± 6.02 | 22.20 ± 8.61 | 14.00 ± 4.98 | 15.83 ± 4.59 | |
Male/female | 10/0 | 11/0 | 9/1 | 8/1 | 11/1 | 12/2 |
BCVA | 1.47 ± 0.68 | 1.42 ± 0.85 | 1.64 ± 0.66 | 1.31 ± 0.77 | 1.17 ± 0.66 | 0.03 ± 0.11 |
mtDNA mutation point (male/female) | G11778A (6/0) | G11778A (5/0) | G11778A (6/1) | G11778A (5/0) | G11778A (5/1) | |
G11778A + G3316A (1/0) | G11778A + G3644A (1/0) | G11778A + G3316A (1/0) | G11778A + T14502C (0/1) | G11778A + G3394C (1/0) | ||
T14484C (1/0) | T14484C (3/0) | T14484C (1/0) | T14484C (3/0) | G11778A + G3644C (1/0) | ||
G3460A (1/0) | G3460A (1/0) | G3460A (1/0) | T14484C (1/0) | |||
C3497T + G3316A (1/0) | G3460A + G3316A (1/0) | G3460A (1/0) | ||||
T14502C (1) | ||||||
T14502C + G3635A (1) | ||||||