Skip to main content

Table 1 Demographic data of patients undergoing optical coherence tomography

From: Characterization of macular thickness changes in Leber’s hereditary optic neuropathy by optical coherence tomography

  LHON patients (N = 52) Normal (N = 14)
≤3 months 3–6 months 6–9 months 9–12 months >12 months
Group 1st 2nd 3rd 4th 5th 6th
Eyes 10 11 10 9 12 14
Age 18.40 ± 7.81 20.27 ± 6.31 22.90 ± 8.66 14.78 ± 5.19 23.08 ± 6.20 28.29 ± 14.64
Age of onset (years) 18.00 ± 8.17 20.09 ± 6.02 22.20 ± 8.61 14.00 ± 4.98 15.83 ± 4.59  
Male/female 10/0 11/0 9/1 8/1 11/1 12/2
BCVA 1.47 ± 0.68 1.42 ± 0.85 1.64 ± 0.66 1.31 ± 0.77 1.17 ± 0.66 0.03 ± 0.11
mtDNA mutation point (male/female) G11778A (6/0) G11778A (5/0) G11778A (6/1) G11778A (5/0) G11778A (5/1)  
G11778A + G3316A (1/0) G11778A + G3644A (1/0) G11778A + G3316A (1/0) G11778A + T14502C (0/1) G11778A + G3394C (1/0)
T14484C (1/0) T14484C (3/0) T14484C (1/0) T14484C (3/0) G11778A + G3644C (1/0)
G3460A (1/0) G3460A (1/0) G3460A (1/0)   T14484C (1/0)
C3497T + G3316A (1/0) G3460A + G3316A (1/0)    G3460A (1/0)
     T14502C (1)
     T14502C + G3635A (1)