Figure 2
From: Lipofuscin accumulation and autophagy in glaucomatous human lamina cribrosa cells
LC cell auto-fluorescence reflecting cellular lipopfuscin content. The lipofuscin auto-fluorescence emitted by approximately 10,000 cells in the yellow-green range of the spectrum (563-607 nm, FL-1 channel) was quantified by flow cytometry. Glaucomatous LC cells demonstrated increased whole cell auto-fluorescence relative to normal LC cells (83.6 ± 45.1 MFI vs. 41.0 ± 3.9 MFI, p = 0.02, n = 3).