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Table 1 This table summarizes the data from Figures 1 B, C and 2 and shows how the number and area of the lipofuscin-like granules and the auto-fluorescence thought secondary to the same was greater in lamina cribrosa cells derived from donors with glaucoma compared to lamina cribrosa cells from donors with no history of glaucoma

From: Lipofuscin accumulation and autophagy in glaucomatous human lamina cribrosa cells

 

NLC Mean ± SD

GLC Mean ± SD

p-value ≤

Number of lipofuscin-like granules (× 10,000 per h.p.f)

2.0 ± 1.3

4.1 ± 1.9

0.002

Area of lipofuscin-like granules (mm2)

23.9 ± 0.3

46.8 ± 2.9

0.007

Autofluorescene (M.F.I.)

41.0 ± 3.9

83.62 ± 45.1

0.02

  1. GLC = Glaucomatous lamina cribrosa, M.F.I Mean flourescene intensity, NLC = Normal lamina cribrosa, SD = Standard deviation.