A hyporeflective space between hyperreflective materials in pigment epithelial detachment and Bruch’s membrane in neovascular age-related macular degeneration

Table 2 Demographic and Clinical Features of Patients with Age-Relate d Macul ar Degeneration and a Hyporeflective space between hyperreflective materials in pigment epithelial detachment and Bruch’s membrane

Patient No	Type of AMD	Treatment	Clinical course of the hyporeflective space	Case with disappearance of the hyporeflective space	Case with recurrence of the hyporeflective space	Accompanied with SRD or CME	Accompanied with RPE tear			Follow up period
		PDT with ranibizumab	Case with the hyporeflective space at initial visit	Case with disappearance of the hyporeflective space	Case with recurrence of the hyporeflective space	Accompanied with SRD or CME	Accompanied with RPE tear	Initial VA	Final VA	Follow up period
1	Occult		+	-	-	+	-	20/250	20/200	10
2	Occult	PDT with ranibizumab	-	+	-	+	+	20/16	20/250	22
3	Occult	PDT with ranibizumab	-	+	-	+	-	20/32	20/25	22
4	Predominantly classic	PDT with ranibizumab	+	+	-	-	-	20/60	20/50	21
5	Occult	PDT with ranibizumab	-	+	-	-	-	20/60	20/200	22
6	Occult	PDT with ranibizumab	-	+	-	+	+	20/200	20/200	9
7	RAP	PDT with ranibizumab	-	-	-	+	+	20/20	20/100	21
8	Occult	PDT with ranibizumab	+	+	-	+	-	20/60	20/250	18
9	Occult	PDT with ranibizumab	-	-	-	+	-	20/80	20/1000	13
10	RAP	PDT with ranibizumab	-	-	-	+	-	20/80	20/60	18
11	Occult	PDT with ranibizumab	+	+	-	+	-	20/125	20/125	17
12	RAP	PDT with ranibizumab	+	+	+	+	-	20/250	20/125	18
13	Predominantly classic	PDT with ranibizumab	-	-	-	-	-	20/20	20/125	22
14	Occult	PDT with ranibizumab	-	-	-	+	-	20/30	20/40	22
15	Occult	PDT with ranibizumab	-	+	-	+	-	20/50	20/40	16
16	Occult	PDT with ranibizumab		+	-	+	-	20/30	20/100	13
17	Occult	PDT with ranibizumab		+	+	+	-	20/125	20/100	14
18	Occult	PDT with ranibizumab	+	+	-	+	-	20/50	20/40	13
19	PCV	PDT with ranibizumab	-	-	-	+	+	h.m	20/30	7
20	Occult	PDT with ranibizumab	+	-	-	+	-	20/40	20/500	12
21	Occult	PDT with ranibizumab	+	+	-	+	-	20/50	20/250	22
22	Occult	ranibizumab	+	+	-	+	+	20/20	20/60	12

AMD = age related macular degeneration; RAP = retinal angiomatous proliferation; PCV = polypoidal choroidal vasculopathy; PDT = photodynamic therapy; SRD = serous retinal detachment; CME = cystoid macular edema; RPE = retinal pigment epithelium H.M = hand motion.

ISSN: 1471-2415