Blood expression levels of chemokine receptor CCR3 and chemokine CCL11 in age-related macular degeneration: a case–control study

Table 2 Demographic data and clinical characteristics of patients included in the study

	nAMD (n = 83)	Controls > 70 years (n = 24)	Controls < 70 years (n = 90)	P-value	Test
Median Age in Years (min-max)	76.0 (63–92)	76.0 (70–85)	53.0 (30–69)	0.001	Kruskal-Wallis test
Male %	45	38	37	0.260	Pearson Chi-square test
Female %	55	62	63
Smoking habits:
Current smokers, (% yes)	24	13	14	0.650	Pearson Chi-square test
Former smokers (% yes)	40	33	41
Never smokers (% yes)	34	50	43
Alcohol intake
Above recommended (% yes)	17	14	13	0.646	Pearson Chi-square test
BMI (median, IQR), kg/m²	25.5 (23.0;28.3)	26.1 (22.3;27.9)	24.5 (21.9;28.5)	0.757	Kruskal-Wallis test
Plasma concentration of CCL11 (median, IQR) pg/ml	516 (342;721)	418 (275;840)	361 (240;503)	0.001	Kruskal-Wallis test

The table shows Demographic data and clinical characteristics of patients in whom plasma concentration of CCL11 was measured. Difference among groups is calculated using Kruskal-Wallis test and Pearson Chi square test. P-values are given.
AMD Age-related Macular Degeneration, nAMD neovascular AMD, IQR Inter Quartile Range, BMI Body Mass Index.

ISSN: 1471-2415