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Table 1 Antibiotic susceptibility 1 of SCUT Isolates of P . aeruginosa and T3SS genotype

From: Cytotoxic clinical isolates of Pseudomonas aeruginosaidentified during the Steroids for Corneal Ulcers Trial show elevated resistance to fluoroquinolones

 

exoU(+) (n = 19)

exoU(-) (n = 75)

P-value2

 

Resistant

Non-resistant

Resistant

Non-resistant

Fluoroquinolones

     

  Ciprofloxacin3

5 (28%)

13 (72%)

1 (1%)

74 (99%)

0.001

  Gatifloxacin

5 (26%)

14 (74%)

2 (3%)

73 (97%)

0.003

  Ofloxacin

6 (32%)

13 (68%)

3 (4%)

72 (96%)

0.002

Cephalosporins

     

  Cefotaxime

3 (16%)

16 (84%)

9 (12%)

66 (88%)

0.70

  Ceftazidime

3 (16%)

16 (84%)

5 (7%)

70 (93%)

0.20

Aminoglycosides

     

  Amikacin

1 (5%)

18 (95%)

1 (1%)

74 (99%)

0.37

  Gentamicin

5 (26%)

14 (74%)

4 (5%)

71 (95%)

0.02

  Tobramycin

3 (16%)

16 (84%)

2 (3%)

73 (97%)

0.054

  1. 1Disc diffusion assay.
  2. 2Fisher’s exact test.
  3. 3Disc diffusion susceptibility data for ciprofloxacin not available for one exoU(+) isolate (n = 18).