From: Low vision due to cerebral visual impairment: differentiating between acquired and genetic causes
Acquired (N = 80) | Genetic (N = 28) | Raw p-value | |
---|---|---|---|
Mean age most recent examination (months) | 70 (SD 58) | 54 (SD 39) | 0.333 |
Affected N/ Available N | Affected N/ Available N | ||
Men | 48/80 (60%) | 17/28 (61%) | 1.00 |
Vigabatrin use | 7/80 (9%) | 2/28 (7%) | 1.00 |
Abnormal MRI | 55/56 (98%) | 11/14 (79%) | 0.023 |
Myopia < -4 | 3/80 (4%) | 0/28 (0%) | 0.567 |
Hypermetropia > +4 | 5/80 (6%) | 3/28 (11%) | 0.425 |
Visual acuity <0.05 or <1.6 cycles/cm at 55 cm | 13/80 (16%) | 7/28 (25%) | 0.396 |
Strabismus | 68/77 (88%) | 18/28 (64%) | 0.009* |
Nystagmus | 31/67 (46%) | 9/26 (35%) | 0.357 |
Visual field defect | 47/65 (72%) | 7/23 (30%) | 0.001* |
Hemianopsia | 10/47 | 1/7 | - |
Upper or lower visual field defect | 19/47 | 3/7 | - |
Constriction of visual field | 18/47 | 3/7 | - |
(Partial) pale optic disc | 51/78 (65%) | 7/26 (27%) | 0.001* |