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Table 3 Selected risk factors for early eye drop bottle exhaustion among patients who report often, usually, or always running out of drops early (at least 5 times yearly)

From: Prevalence of self-reported early glaucoma eye drop bottle exhaustion and associated risk factors: a patient survey

Factor

Yes, runs out

No, does not

P

Age (yrs)

71.7 ± 11.3

67.1 ± 14.2

.271*

Years of glaucoma drop use

10.9 ± 7.6

7.8 ± 5.8

.070*

Poor visual acuity (≤20/70)

   

    Better eye

2/12 (16.7%)

7/224 (3.1%)

.070†

    Worse eye

6/46 (13.0%)

6/190 (3.2%)

.015†

logMAR visual acuity

   

    Better eye

.505 ± 1.03

.087 ± .199

.188*

    Worse eye

.881 ± 1.06

.397 ± .787

.043*

Visual field

   

    Mean deviation (dB), better eye

−6.7 ± 7.6

−4.1 ± 5.6

.131*

    Visual Field Index, better eye

81 ± 21

90 ± 16

.198*

    Mean deviation, worse eye

−12.0 ± 13.3

−8.4 ± 7.8

.387*

    Visual Field Index, worse eye

63 ± 40

78 ± 23

.228*

Number of comorbid conditions (mean ± SD)

2.8 ± 2.0

2.3 ± 1.8

.274*

Number of prescription medications (not including eye drops)

5.3 ± 5.4

3.2 ± 3.0

.228*

Number of bottles

2.1 ± 1.2

2.1 ± 0.8

.962†

Number of eye drops/day

6.2 ± 4.5

6.6 ± 3.8

.235†

  1. *t-test, 2-tail; †Chi square or Fisher Exact test, 2-tail.