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Table 9 Haplotype association analysis in cases and controls

From: Associations of complement factor B and complement component 2 genotypes with subtypes of polypoidal choroidal vasculopathy

Polypoidal CNV vs. control
Haplotypes %   
rs541862 rs2072633 rs4151667 Polypoidal CNV Control Chi-Squ p-value
T A T 63% 42% 22.177 <0.0001*
C A T 0% 9% 14.9366 0.0001*
T G T 35% 47% 7.9166 0.0049*
C G T 2% 0% 13.5581 0.0002*
T G A 0% 2% 3.9293 0.0475*
Typical PCV vs. control
Haplotypes %   
rs541862 rs2072633 rs4151667 Typical PCV Control Chi-Square p-value
T A T 57% 42% 20.5614 <0.0001*
C A T 0% 9% 34.8144 <0.0001*
T G T 37% 47% 9.3704 0.0022*
C G T 6% 0% 33.5324 <0.0001*
Polypoidal CNV vs. typical PCV
Haplotypes %   
rs541862 rs2072633 rs4151667 Typical PCV Polypoidal CNV Chi-Squ p-value
T A T 57% 63% 1.5687 0.2104
C A T 0% 0% 0 1
T G T 36% 33% 0.3302 0.5656
C G T 6% 2% 3.0395 0.0813
T A A 0% 2% 7.1092 0.0077*
C A A 0% 0% 0 1
T G A 1% 0% 2.1402 0.1435
C G A 0% 0% 0 1
  1. *p-value > 0.05 calculated by chi-square analysis.