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Table 3 Area under the receiver operating characteristic curve, sensitivity and specificity for known and novel angle-closure-detection parameters for detecting angle closure

From: Relative lens vault in subjects with angle closure

 

AUROC (95% CI)

Optimal Cutoff Point+

Sensitivity++(95% CI)

Specificity++(95% CI)

Known Parameters

LV

0.92 (0.86, 0.96)

0.75

95.2 (91.1, 98.5)

74.6 (64.5, 84.0)

ACD

0.83 (0.76, 0.88)

0.63

88.3 (85.7, 92.1)

73.7 (66.2, 78.0)

Axial length

0.73 (0.67, 0.80)

0.53

72.0 (67.1, 77.5)

68.8 (62.4, 74.3)

Novel Parameters

Anterior vault

0.76 (0.67, 0.81)

0.60

83.7 (74.2, 86.7)

71.1 (67.7, 74.6)

 

Relative LV*

0.97 (0.93, 0.99)

0.85

98.7 (94.3, 100.0)

86.0 (76.9, 91.5)

  1. AUROC = area under the receiver operating characteristic curve; CI = confidence interval; LV = lens vault; ACD = anterior chamber depth.
  2. *Relative LV = LV/Anterior vault.
  3. +given by the maximum of the Youden index, calculated as J = max(sensitivity + specificity-1).
  4. ++sensitivity and s.