Table 4 Odds ratio from fitting the LogitBoost logistic regression on the AMD diagnosis outcome (dataset imputing missing values with population’s mean/mode)
Variable (mode) | Odds ratio | Lower 95% CI | Upper 95% CI | P-value |
|---|---|---|---|---|
Age (per year older) | 1.09 | 1.07 | 1.11 | <0.0001 |
Gender (M vs F) | 1.05 | 0.71 | 1.57 | 0.7985 |
Soft drusen (pos vs neg) | 19.30 | 7.82 | 47.65 | <0.0001 |
Macular scar (pos vs neg) | 1.75 | 0.57 | 5.41 | 0.329 |
RPE defect/pigment mottling (pos vs neg) | 2.20 | 1.20 | 4.04 | 0.0109 |
Depigmentation area (pos vs neg) | 1.35 | 0.73 | 2.51 | 0.3349 |
Subretinal fluid (pos vs neg) | 3.21 | 1.70 | 6.08 | 0.0003 |
Macular tickness (per unit increase) | 1.00 | 0.99 | 1.00 | 0.139 |
Subretinal fibrosis (pos vs neg) | 4.60 | 1.39 | 15.24 | 0.01245 |
Subretinal hemorrhage (pos vs neg) | 5.91 | 1.49 | 23.42 | 0.01138 |