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Table 2 Comparison of intraocular, systemic and perfusion pressures (mmHg) in the 2 groups

From: Comparison of the effects of bimatoprost and a fixed combination of latanoprost and timolol on 24-hour blood and ocular perfusion pressures: the results of a randomized trial

 

Bimatoprost

LTFC

p-value

Baseline IOP (sd)

16.3 (3.3)

15.5 (2.9)

0.2

Baseline nocturnal IOP (sd)

16.9 (3.6)

16.0 (3.3)

0.3

Baseline SBP (sd)

136.5 (18.3)

134.2 (20.1)

0.1

Baseline DBP (sd)

79.1 (10.2)

78.2 (10.1)

0.4

Baseline nocturnal SBP (sd)

121.0 (13.8)

122.1 (15.8)

0.3

Baseline nocturnal DBP (sd)

72.7 (7.9)

73.2 (9.5)

0.4

Baseline SPP (sd)

120.2 (15.7)

118.7 (16.8)

0.3

Baseline DPP (sd)

62.8 (6.9)

62.7 (8.2)

0.6

Baseline nocturnal SPP (sd)

104.1 (13.1)

106.1 (16.4)

0.2

Baseline nocturnal DPP (sd)

55.8 (8.0)

57.2 (12.1)

0.1

12 week IOP (sd)

16.1 (2.5)

16.3 (3.7)

0.7

12 week nocturnal IOP (sd)

16.1 (2.6)

16.1 (3.9)

0.8

Holter SBP (sd)

135.1 (16.7)

128.1 (15.3)

0.04

Holter DBP (sd)

79.5 (8.3)

78.7 (11.8)

0.4

Holter nocturnal SBP (sd)

124.8 (14.4)

120.0 (14.5)

0.08

Holter nocturnal DBP (sd)

71.7 (7.9)

70.6 (11.3)

0.2

Holter SPP (sd)

119.0 (10.8)

111.8 (15.3)

0.03

Holter DPP (sd)

63.4 (8.0)

62.4 (11.1)

0.1

Holter nocturnal SPP (sd)

108.7 (14.4)

103.9 (17.3)

0.07

Holter nocturnal DPP (sd)

55.6 (7.4)

54.5 (12.3)

0.2

  1. LTFC: latanoprost/timolol fixed combination; IOP: intraocular pressure; sd: standard deviation; SBP: systolic blood pressure; DBP: diastolic blood pressure; SPP: systolic perfusion pressure; DPP: diastolic perfusion pressure.