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Figure 5 | BMC Ophthalmology

Figure 5

From: Oxidative stress causes ERK phosphorylation and cell death in cultured retinal pigment epithelium: Prevention of cell death by AG126 and 15-deoxy-delta 12, 14-PGJ2

Figure 5

Prevention of H2O2 induced cytotoxicity by 15d-PGJ2 in RPE cells. Fig. 5A: Primary RPE cells were pretreated with various concentrations of 15d-PGJ2 overnight, followed by 1.3 mM or 1.4 mM H2O2 for 1 day (without 15d-PGJ2), then processed for the MTT viability assay. Fig. 5B: ARPE-19 cells were pretreated with 1 μM 15d-PGJ2 overnight, followed by various concentrations of H2O2 for 1 day (without 15d-PGJ2), then processed for the MTT viability assay. Statistical analyses were performed comparing cells treated with H2O2 alone versus H2O2 plus 15d-PGJ2.

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BMC Ophthalmology

ISSN: 1471-2415

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