Table 3 Comparison of clinical, histologic features and degree of keratocyte loss in various types of corneal infections
From: Keratocyte loss in corneal infection through apoptosis: a histologic study of 59 cases
Features | Etiology | Correlation of apoptosis with clin/hist features | ||||
|---|---|---|---|---|---|---|
| Â | Â | Fungus (22) | Virus (15) | Bacteria (14) | Acanth (8) | Â |
Size of ulcer (38) | Small (≤2 mm2) | 1 (6.7%) | 2 (28.6%) | 1 (9.1%) | 2 (40.0%) | P = 0.224 |
|  | Medium and Large (≥25 mm2) | 14 (63.63%) | 5 (33.33%) | 10 (71.4%) | 3 (37.5%) |  |
Stromal thinning (43) | Absent | 10 (62.5%) | 3 (42.9%) | 6 (42.8%) | 5 (83.3%) | P = 0.313 |
| Â | Present | 6 (37.5%) | 4 (57.1%) | 8 (57.1%) | 1 (16.7%) | Â |
Necrosis (59) | Absent | 0 | 8 (53.3%) | 2 (14.3%) | 1 (12.5%) | NA |
| Â | Present | 22 (100%) | 7 (46.7%) | 12 (85.7%) | 7 (87.5%) | NA |
Inflammation (59) | Mild/Moderate | 6 (27.3%) | 10 (66.7%) | 7 (50.0%) | 5 (62.5%) | P = 0.087 |
| Â | Severe | 16 (72.7%) | 5 (33.3%) | 7 (50.0%) | 3 (37.5%) | Â |
Keratocytes (57) | Absent | 4 (19.1%) | 4 (28.6%) | 0 | 0 | NA |
| Â | Reduced | 15 (71.4%) | 10 (71.4%) | 14 (100%) | 8 (100%) | Â |
| Â | Normal | 2(9.5%) | 0 | 0 | 0 | Â |
Apoptosis (54) | Absent | 0 | 1 (6.7%) | 0 | 0 | NA |
| Â | Present | 19 (100%) | 14 (93.3%) | 14 (100%) | 6 (100%) | Â |