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Table 3 Comparison of clinical, histologic features and degree of keratocyte loss in various types of corneal infections

From: Keratocyte loss in corneal infection through apoptosis: a histologic study of 59 cases

Features Etiology Correlation of apoptosis with clin/hist features
   Fungus (22) Virus (15) Bacteria (14) Acanth (8)  
Size of ulcer (38) Small (≤2 mm2) 1 (6.7%) 2 (28.6%) 1 (9.1%) 2 (40.0%) P = 0.224
  Medium and Large (≥25 mm2) 14 (63.63%) 5 (33.33%) 10 (71.4%) 3 (37.5%)  
Stromal thinning (43) Absent 10 (62.5%) 3 (42.9%) 6 (42.8%) 5 (83.3%) P = 0.313
  Present 6 (37.5%) 4 (57.1%) 8 (57.1%) 1 (16.7%)  
Necrosis (59) Absent 0 8 (53.3%) 2 (14.3%) 1 (12.5%) NA
  Present 22 (100%) 7 (46.7%) 12 (85.7%) 7 (87.5%) NA
Inflammation (59) Mild/Moderate 6 (27.3%) 10 (66.7%) 7 (50.0%) 5 (62.5%) P = 0.087
  Severe 16 (72.7%) 5 (33.3%) 7 (50.0%) 3 (37.5%)  
Keratocytes (57) Absent 4 (19.1%) 4 (28.6%) 0 0 NA
  Reduced 15 (71.4%) 10 (71.4%) 14 (100%) 8 (100%)  
  Normal 2(9.5%) 0 0 0  
Apoptosis (54) Absent 0 1 (6.7%) 0 0 NA
  Present 19 (100%) 14 (93.3%) 14 (100%) 6 (100%)  
  1. NA = Not applicable