Longitudinal analysis of serum anti-recoverin antibodies in three CAR patients from serum samples obtained during follow-up clinic visits. Patients' antibody levels were measured by ELISA using recoverin-coated plates. (A) 61-year-old woman (P403) diagnosed with endometrial cancer in 1991. The graph presents tests performed after the original publication of this case report in 1998 . Tolpa is a natural immunosuppressive drug. (B) 64-year-old woman (P718) who was diagnosed with breast carcinoma in 2002 who experienced an onset of visual loss 6 months later. (C) 62-year-old man (P409) who presented with an onset of visual loss and antibodies before the diagnosis of SCCL in 1995. Note that chemotherapy and radiation completely diminished the presence of antibodies due to the damage of the immune cells. The level of antibodies increased after the immune system recovered.