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Table 1 Frequency distribution of p21 codon 31 polymorphisms in POAG patients and healthy subjects. "Ser" and "Arg " represent encoding of Serine and Arginine, respectively, from the polymorphic site on exon 2.

From: A polymorphism at codon 31 of gene p21 is not associated with primary open angle glaucoma in Caucasians

 

Ser/Ser

Ser/Arg

Arg/Arg

Total

POAG (n = 140)

128 (91.4%)

10 (7.1%)

2 (1.5%)

140

Controls (n = 73)

61 (83.6%)

12 (16.4%)

0 (0.0%)

73

Total

189 (88.8%)

22 (10.3%)

2 (0.9%)

213

  1. Fisher's exact test: The two-tailed P value equals 0.0561. (Note: The frequencies of the Arg homozygotes were excluded from the analysis, as they were very low in the POAG group and 0 in the control group)
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BMC Ophthalmology

ISSN: 1471-2415

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