Skip to main content

Table 2 Influence of latanoprost on retrobulbar hemodynamics. Influence of latanoprost on ocular perfusion. Overview of the results from CDI measurements before and one month after regular application of latanoprost: Increase of blood flow velocities were statistically not significant (n = 10). Bold printed measures were subjected to statistical testing; all other parameters were observational only.

From: Effects of glaucoma drugs on ocular hemodynamics in normal tension glaucoma: a randomized trial comparing bimatoprost and latanoprost with dorzolamide [ISRCTN18873428]

   PSV (cms-1) EDV (cms-1) RI PI
OA before latanoprost 31.7 ± 3.1 4.6 ± 0.9 0.87 ± 0.02 2.59 ± 0.15
  after latanoprost 39.0 ± 10.1 6.2 ± 1.2 0.83 ± 0.01 2.14 ± 0.09
CRA before latanoprost 7.6 ± 0.6 1.5 ± 0.1 0.78 ± 0.01 1.96 ± 0.10
  after latanoprost 8.4 ± 0.9 1.7 ± 0.1 0.79 ± 0.02 1.95 ± 0.13
SPCA before latanoprost 8.6 ± 1.8 1.8 ± 0.2 0.74 ± 0.03 1.75 ± 0.13
  after latanoprost 9.5 ± 1.1 2.5 ± 0.4 0.73 ± 0.03 1.60 ± 0.11
LPCA before latanoprost 13.1 ± 1.5 2.5 ± 0.3 0.81 ± 0.02 1.96 ± 0.14
  after latanoprost 13.0 ± 1.9 2.5 ± 0.4 0.78 ± 0.04 1.90 ± 0.21
  1. Abbreviations: OA – Ophthalmic artery, CRA – central retinal artery, SPCA – short posterior ciliary artery, LPCA – long posterior ciliary artery, PSV – peak systolic velocity, EDV – enddiastolic velocity, RI – resistive index, PI – pulsatility index.