Skip to main content

Table 3 Changes in Contrast Sensitivity (Log CS) at Different Levels of Illumination Ω

From: Lutein supplementation in retinitis pigmentosa: PC-based vision assessment in a randomized double-masked placebo-controlled clinical trial [NCT00029289]

Level of Illumination

Normal (100%)

Low (4%)

Very Low (0.1%)

Covariates§

Coefficient¶ (95% CI)

P value

Coefficient (95% CI)

P value

Coefficient (95% CI)

P value

Treatment†

0.0154 (-0.0164,0.0471)

0.342

0.0408 (-0.0273,0.1089)

0.241

-0.0184 (-0.0545, 0.0176)

0.316

Period

0.0351 (0.0025,0.0677)

0.035

0.0014 (-0.0853,0.0880)

0.975

-‡

-

Time† (number of weeks)

0.0008 (-0.0008, 0.0025)

0.313

0.0001 (-0.0034, 0.0037)

0.934

-0.0009 (-0.0024,0.0006)

0.237

Age

-‡

-

-0.0049 (-0.0061,-0.0038)

<0.001

-

-

Vitamin A Use

-

-

-

-

-

-

Iris color

-

-

-

-

-

-

Period × Treatment

-

-

-

-

-

-

Treatment × Time

-

-

-

-

-

-

Period × Time

-

-

-0.0028 (-0.0055,-0.0001)

0.042

-

-

Baseline Log CS

0.9865 (0.9289, 1.0440)

<0.001

0.9451 (0.8496, 1.0406)

<0.001

0.9721 (0.9003,1.0440)

<0.001

Intercept

0.0133 (-0.0705, 0.0971)

0.755

0.2781 (0.1374,0.4188)

<0.001

0.459 (-0.0119, 0.1037)

0.119

  1. Ω Variables and model criteria: See Table 2.
  2. ¶ The coefficient indicates the change in Log CS units per unit change in the covariate.