Lutein supplementation in retinitis pigmentosa: PC-based vision assessment in a randomized double-masked placebo-controlled clinical trial [NCT00029289]

Table 4 Visual field regression model. Ω

Model	Without 6-Week Delay Assumption		With 6-Week Delay Assumption
Covariates^§	Coefficient¶ (95% CI)	P value	Coefficient (95% CI)	P value
Treatment^†	0.0183 (0.0010,0.0355)	0.038	0.0292 (0.0118,0.0466)	0.001
Period	-^‡	-	-	-
Time^† (number of weeks)	-0.0022 (-0.0034,-0.0010)	<0.001	-0.0023 (-0.0034,-0.0011)	<0.001
Age	-	-	-	-
Vitamin A Use	0.0937 (0.0081, 0.1793)	0.032	0.0941 (0.0080, 0.1803)	0.032
Iris color	-	-	-	-
Period × Treatment	-	-	-	-
Treatment × Time	-	-	-	-
Period × Time	-	-	-	-
Baseline Log Retinal Area	0.8965 (0.8309, 0.9621)	<0.001	0.8957 (0.8297, 0.9617)	<0.001
Intercept	0.1325 (0.0583, 0.2067)	<0.001	0.1299 (0.0554,0.2043)	0.001

Ω For description of variables and coefficients: See Table 2.
¶ The coefficient indicates the change in log (visual field area) per unit change in the covariate.

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