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Table 3 Prediction of the average intraocular pressure during binocular treatment in the initially untreated eye (eye 2) by multivariable linear regression.

From: Interpretation of uniocular and binocular trials of glaucoma medications: an observational case series

Cases (n, r2, Intercept).

IOP, eye 1

IOP, eye 2

 

Last baseline.

During Trial.

Baseline.

...change with uniocular trial.

 

Time A.

Time B.

Time A.

Time B – A.

 

(b, p)

(b, p)

(b, p)

(b, p, p*)

All cases (96, 0.49, 5.4)

(-0.002, 0.98)

(0.19, 0.07)

(0.42, <0.001)

(0.07, 0.50, 0.53)

Baseline untreated (64, 0.47, 5.6)

(-0.01, 0.94)

(0.14, 0.30)

(0.44, 0.004)

(0.10, 0.54, 0.55)

Baseline treated (32, 0.56, 4.4)

(0.03, 0.82)

(0.24, 0.17)

(0.41, 0.006)

(0.06, 0.72, 0.80)

Latanoprost (56, 0.41, 5.4)

(0.05, 0.81)

(-0.004, 0.98)

(0.50, 0.03)

(0.25, 0.19, 0.23)

Timolol only (19, 0.62, 6.0)

(0.02, 0.89)

(0.47, 0.04)

(0.14, 0.47)

(0.04, 0.86, 0.72)

Dorzolamide only (8, 0.90, 2.1)

(0.38, 0.03)

(0.06, 0.84)

(0.78, 0.01)

(0.71, 0.03, 0.04)

Brimonidine (10, 0.66, 4.6)

(0.17, 0.58)

(0.04, 0.92)

(0.39, 0.23)

(0.04, 0.90, 0.86)

  1. *p value for regression to predict square root of IOP, eye 2.