Skip to main content

Table 5 Predictors of the average intraocular pressure during binocular use in the subsequently treated eye (eye 2) following a uniocular trial and subsequent binocular trial of medication by multivariable linear regression.

From: Interpretation of uniocular and binocular trials of glaucoma medications: an observational case series

Cases...trial type (r 2, r2*, Intercept).

IOP, eye 1

IOP, eye 2

 

Last baseline.

During Trial.

Baseline.

Change with trial.

 

Time A

Time B

Time A

Time B – A.

 

(b, p)

(b, p)

(b, p)

(b, p)

All cases (n = 70). Trial type...

    

   ...uniocular (0.39, 0.39, 5.4)

(0.11, 0.27)

(0.16, 0.22)

(0.33, 0.008)

(0.13, 0.37)

   ...binocular (0.38, 0.39, 6.0)

(0.17, 0.14)

(-0.10, 0.60)

(0.51, 0.003)

(0.35, 0.12)

Baseline untreated (n = 48). Trial type...

    

   ...uniocular (0.40, 0.42, 4.8)

(0.04, 0.80)

(0.15, 0.40)

(0.44, 0.03)

(0.12, 0.57)

   ...binocular (0.40, 0.43, 5.0)

(0.07, 0.70)

(-0.09, 0.72)

(0.67, 0.008)

(0.35, 0.24)

Baseline treated (n = 22). Trial type...

    

   ...uniocular (0.37, 0.36, 6.8)

(0.14, 0.31)

(0.12, 0.60)

(0.28, 0.10)

(0.19, 0.43)

   ...binocular (0.37, 0.36, 7.9)

(0.24, 0.17)

(-0.19, 0.58)

(0.42, 0.09)

(0.38, 0.28)

  1. * r2 value for regression to predict square root of IOP, eye 2.