18S rRNA PCR assay | Microscopy and Culture | Total |
---|
 | Positive | Negative |  |
---|
Positive | 10 | 1 | 11 |
Negative | 1 | 18 | 19 |
Total
| 11 | 19 | 30 |
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a. True positive = 10, false positive = 1, false negative = 1, true negative = 18.
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b. This leads to estimates of sensitivity = 0.91 (95% CI = 0.59 to 1.00), specificity = 0.95 (95% CI = 0.74 to 1.00) and a diagnostic odds ratio (DOR) of 180 (7.8 to 8195.8).
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c. The positive likelihood ratio (LR+) is 17.3 (95% CI = 2.5 to 117.4) and the negative likelihood ratio (LR-) is 0.10 (95% CI = 0.03 to 0.36).