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Table 1 expression data for CD133+ retinal progenitor cell phenotype

From: CD133+adult human retinal cells remain undifferentiated in Leukaemia Inhibitory Factor (LIF)

mRNA Description

Mean Expression

Homo sapiens prominin 1 (PROM1), mRNA.

6795

Homo sapiens nestin (NES), mRNA.

215

Homo sapiens fms-related tyrosine kinase 3 (FLT3), mRNA. (CD135)

66

Homo sapiens Thy-1 cell surface antigen (THY1), mRNA. (CD90)

390

Homo sapiens nerve growth factor receptor (TNFR superfamily, member 16) (NGFR), mRNA. (CD271)

542

Homo sapiens neural cell adhesion molecule 1 (NCAM1), transcript variant 2, mRNA.

1987

Homo sapiens paired box 6 (PAX6), transcript variant 1, mRNA.

788

Homo sapiens ATP-binding cassette, sub-family G (WHITE), member 2 (ABCG2), mRNA.

146

Homo sapiens doublecortex; lissencephaly, X-linked (doublecortin) (DCX), transcript variant 1, mRNA.

258

Homo sapiens rhodopsin (RHO), mRNA.

16078

Homo sapiens glial fibrillary acidic protein (GFAP), mRNA.

637

Homo sapiens leukemia inhibitory factor receptor alpha (LIFR), mRNA.

1737

Homo sapiens Notch homolog 1, translocation-associated (Drosophila) (NOTCH1), mRNA.

326

Homo sapiens recoverin (RCVRN), mRNA.

10323

Homo sapiens platelet/endothelial cell adhesion molecule (CD31 antigen) (PECAM1), mRNA.

188

Homo sapiens protein tyrosine phosphatase, receptor type, C (PTPRC), transcript variant 1, mRNA. (CD45)

38

Homo sapiens retinaldehyde binding protein 1-like 1 (RLBP1L1), mRNA (CRALBP1)

256

Homo sapiens vimentin (VIM), mRNA.

2709

Homo sapiens CD34 molecule (CD34), transcript variant 2, mRNA.

123

Homo sapiens KIT ligand (KITLG), transcript variant b, mRNA. (CD117)

136

Homo sapiens Nanog homeobox (NANOG), mRNA.

111

Homo sapiens neurofilament, medium polypeptide 150 kDa (NEFM), transcript variant 1, mRNA.

662

Homo sapiens cyclin D1 (CCND1), mRNA.

369

Homo sapiens antigen identified by monoclonal antibody Ki-67 (MKI67), mRNA.

55

  1. RNA was isolated from magnetically separated CD133+ cells and prepared using the Affymetrix whole transcript (WT) assay. Mean expression values represent 3 repeats of actively transcribing genes (GEO series record GSE14733). Although expressivity has varying values with respect to extent of protein expression via FACS analysis, we do not make comparisons at this level. Levels of mRNA are not directly proportional to the expression level of the proteins [30]. The number of protein molecules synthesized using a given mRNA molecule as a template is highly dependent on translation-initiation features of the mRNA sequence. In addition proteins may differ substantially in their in vivo half lives [30].