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Figure 9 | BMC Ophthalmology

Figure 9

From: αA-crystallin R49Cneomutation influences the architecture of lens fiber cell membranes and causes posterior and nuclear cataracts in mice

Figure 9

Immunofluorescence analysis of fiber cells in wild type and R49C neo /R49C neo knock-in lenses. Immunofluorescence staining of lens sections with an antibody to membrane intrinsic protein MIP and an Alexa568-conjugated secondary antibody (red) revealed a normal fiber cell morphology in wild type lenses (A), whereas the R49Cneo/R49Cneo lenses (B) showed disorganized fiber cells and swollen cells (arrows) enclosed by membranes. Nuclei are shown by arrowheads.

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BMC Ophthalmology

ISSN: 1471-2415

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