TY - JOUR AU - Khoh-Reiter, Su AU - Jessen, Bart A. PY - 2009 DA - 2009/07/28 TI - Evaluation of the cytotoxic effects of ophthalmic solutions containing benzalkonium chloride on corneal epithelium using an organotypic 3-D model JO - BMC Ophthalmology SP - 5 VL - 9 IS - 1 AB - Benzalkonium chloride (BAC) is a common preservative used in ophthalmic solutions. The aim of this study was to compare the cytotoxic effects of BAC-containing ophthalmic solutions with a BAC-free ophthalmic solution using an organotypic 3-dimensional (3-D) corneal epithelial model and to determine the effects of latanoprost ophthalmic solution and its BAC-containing vehicle on corneal thickness in a monkey model. SN - 1471-2415 UR - https://doi.org/10.1186/1471-2415-9-5 DO - 10.1186/1471-2415-9-5 ID - Khoh-Reiter2009 ER -