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Figure 4 | BMC Ophthalmology

Figure 4

From: Evaluation of the cytotoxic effects of ophthalmic solutions containing benzalkonium chloride on corneal epithelium using an organotypic 3-D model

Figure 4

Corneal thickness measurements from 1-year monkey studies. (A) Effect of topical administration of latanoprost vehicle containing 0.2 mg/mL (0.02%) benzalkonium chloride on corneal thickness in monkeys. p > 0.4 for vehicle-treated versus untreated eyes in both male and female monkeys at all time points. PD = predose. (B) Effect of the topical administration of suprapharmacologic doses of latanoprost (100 μg/day) on corneal thickness in monkeys. p > 0.5 for the vehicle-treated versus latanoprost-treated eyes in both male and female monkeys at all time points. PD = predose.

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