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Table 3 Schirmer test, fluorescein staining, and lissamine green staining at baseline and after cataract surgery

From: Efficacy of 1% carboxymethylcellulose sodium for treating dry eye after phacoemulsification: results from a multicenter, open-label, randomized, controlled study

Clinical assessment Treatment group Control group P value *
n Score n Score
Schirmer test, mm (mean ± SD)
  Baseline 90 12.6 ± 6.9 90 12.9 ± 6.9 0.6800
  At day 7 85 11.8 ± 5.6 85 12.5 ± 6.8 0.6620
  At day 30 83 12.7 ± 6.1 82 12.6 ± 6.5 0.6929
  Change from baseline at day 7 85 −0.8 ± 5.9 85 −0.3 ± 5.1 0.9055
  Change from baseline at day 30 83 0.0 ± 5.4 82 −0.1 ± 5.6 0.6889
Fluorescein staining score (mean ± SD)
  Baseline 90 2.0 ± 2.8 90 1.7 ± 2.6 0.4084
  At day 7 85 2.0 ± 2.8 85 1.8 ± 2.6 0.7092
  At day 30 83 1.1 ± 1.8 82 1.2 ± 1.9 0.3984
  Change from baseline at day 7 85 0.0 ± 1.7 85 0.0 ± 1.9 0.5236
  Change from baseline at day 30 83 −1.0 ± 2.3**** 82 −0.6 ± 2.0*** 0.2207
Lissamine staining score (mean ± SD)
  Baseline 90 2.9 ± 3.2 90 2.7 ± 3.1 0.6162
  At day 7 85 2.9 ± 3.3 85 2.6 ± 3.2 0.7955
  At day 30 83 2.1 ± 2.4 82 2.3 ± 2.6 0.4380
  Change from baseline at day 7 85 −0.2 ± 2.5 85 −0.3 ± 2.8 0.7685
  Change from baseline at day 30 83 −1.0 ± 2.6**** 82 −0.6 ± 2.6** 0.2404
  1. SD, standard deviation.
  2. *P values for the difference between groups calculated using Wilcoxon rank sum test.
  3. **P = 0.0268; ***P = 0.0070; ****P ≤ 0.0004 for change from baseline calculated using Wilcoxon signed rank test.
  4. Significant changes from baseline are indicated in bold font.