Efficacy of 1% carboxymethylcellulose sodium for treating dry eye after phacoemulsification: results from a multicenter, open-label, randomized, controlled study

Table 4 OSDI questionnaire and patient subjective symptom evaluation scores at baseline and after cataract surgery

Subject assessment	Treatment group		Control group		P value*
Subject assessment	n	Score	n	Score	P value*
OSDI questionnaire score (mean ± SD)
Baseline	90	41.8 ± 20.8	90	44.8 ± 20.9	0.2116
At day 7	85	15.6 ± 16.8	85	18.1 ± 19.5	0.4934
At day 30	83	12.7 ± 11.3	82	14.2 ± 13.8	0.7243
Change from baseline at day 7	85	−26.7 ± 20.3**	85	−27.2 ± 22.7***	0.7447
Change from baseline at day 30	83	−29.9 ± 19.4***	82	−30.8 ± 20.6***	0.7748
Subjective symptom evaluation score (mean ± SD)
Baseline	90	11.8 ± 6.2	90	11.5 ± 6.0	0.7700
At day 7	85	6.1 ± 5.3	85	6.4 ± 5.2	0.4737
At day 30	83	5.1 ± 3.6	82	5.6 ± 4.0	0.5971
Change from baseline at day 7	85	−5.9 ± 5.2**	85	−5.4 ± 5.6***	0.9018
Change from baseline at day 30	83	−7.0 ± 4.7**	82	−6.2 ± 5.8***	0.6069

OSDI, Ocular Surface Disease Index; SD, standard deviation.
*P values for the difference between groups calculated using Wilcoxon rank sum test except for OSDI. Change from baseline at day 30 calculated using t-test.
**P < 0.0001 for change from baseline calculated using Wilcoxon signed rank test.
***P < 0.0001 for change from baseline calculated using paired t-test.
Significant changes from baseline are indicated in bold font.

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