Table 3 Frequency of alleles and genotypes of CFH Rs1061170, HTRA1 Rs11200638 and C3 Rs2230199 SNPs among patients
No. (%)* | Final CPT (μ) ± SEM | P value | Final CST (μ) ± SEM | P value | Change in CPT (μ) ± SEM | P value | Change in CSF (μ) ± SEM | P value | |
|---|---|---|---|---|---|---|---|---|---|
CFH | |||||||||
TT (WT) | 31 (70.5) | 284.4 ± 24.0 | 0.007 | 312.0 ± 17.4 | 0.006 | −92.6 ± 26.43 | 0.009 | −76.8 ± 22.01 | 0.015 |
CC + TC (AT RISK) | 13 (29.5) | 459.3 ± 76.8 | 460.3 ± 67.5 | 79.9 ± 74.84 | 66.9 ± 70.38 | ||||
HTRA1 | |||||||||
GG (WT) | 14 (35.9) | 378.1 ± 35.7 | 0.57 | 378.1 ± 27.0 | 0.79 | 2.57 ± 35.83 | 0.49 | −8.29 ± 32.75 | 0.669 |
AA + GA (AT RISK) | 25 (64.1) | 338.4 ± 47.8 | 362.8 ± 40.7 | −47.54 ± 50.50 | −36.21 ± 45.38 | ||||
C3 | |||||||||
CC (WT) | 27 (60) | 331.1 ± 40.6 | 0.95 | 364.2 ± 36.4 | 0.87 | −52.04 ± 42.88 | 0.814 | −29.81 ± 40.89 | 0.964 |
GG + GC (AT RISK) | 18 (40) | 326.6 ± 63.2 | 354.1 ± 50.7 | −33.63 ± 70.62 | −26.6 ± 61.255 |