Figure 4

Optical coherence tomography (OCT) results of the retinal nerve fiber layer (RNFL) during the experimental periods. A, OCT result of the normal RNFL; B and C, OCT results of the RNFL in Group A at 1 day and 7 days after modeling with 0.5 mL of normal saline administration. An obvious swelling was observed in RNFL; D and E, OCT results of the RNFL in Group B at 1 day and 7 days after modeling, with 0.5 mL of DMSO administration; F and G, OCT results of the RNFL in Group D at 1 day and 7 days after modeling, with 0.5 mL of 1 g/L BN52021 administration; H and I, OCT results of the RNFL in Group E at 1 day and 7 days after modeling, with 0.5 mL of 5 g/L BN52021 administration. Comparing with the normal RNFL, all RNFLs in the experimental groups were swelling to some extent. For A, D and G, bar = 150 μm, for B, C, E, F, H and I, bar = 175 μm.