Comparing the effectiveness and costs of Bevacizumab to Ranibizumab in patients with Diabetic Macular Edema: a randomized clinical trial (the BRDME study)

Table 3 Study flow chart

Assessment/	Phase	Treatment
procedure	Visit	1	2	3	4	5	6	7	8
	Month	0		1	2	3	4	5	6
Check inclusion/exclusion criteria		X
Informed consent		X
Medical History		X
Vital Signs		X		X	X	X	X	X	X
Check concomitant medications		X	X	X	X	X	X	X	X
Check adverse events			X	X	X	X	X	X	X
EQ-5D or HUI-3 questionnaire			X			X			X
Blood sample		X
Drug administration			X	X	X	X	X	X
BCVA		X	X	X	X	X	X	X	X
Ophthalmic exam		X	X						X
Fluorescein angiography		X							X
Optical coherence tomography		X	X	X	X	X	X	X	X

ISSN: 1471-2415