Table 1 Base case settings of the BIM
Variables | Details |
|---|---|
Country and perspective | United Kingdom; NHS and PSS perspective |
Currency | GB 2013 £ |
Time horizon | 5 years |
Intervention | Aprokam vials of 50 mg, reconstituted into one single 1 mg/0.1 mL individual dose administered intracamerally by slow injection into the anterior chamber of the eye [9]. Resource utilisation inputs used in the model for the reconstitution of Aprokam follow the Aprokam SPC guidelines [9] |
Comparators | PFS of cefuroxime prepared in the pharmacy hospital, using Zinacef 750 mg vials |
Refrigerated ready-to-use PFS purchased by the hospital from manufacturers | |
Number of cataract surgeries in first year | Hypothetical cohort of 1000 cataract surgeries performed in the first year |
Annual increase in cataract surgeries | Annual increase of 5.2 % in the number of cataract surgeries. This is based on the average annual increase in the number of cataract surgeries performed within the NHS in England between 1998 and 2009, as reported by The Royal College of Ophthalmologists [6] |