Table 2 Association between GSTM1 or GSTT1 polymorphism and cataract risk
Groups | Na | Statistical methodb | OR (95 % CI) | P |
|---|---|---|---|---|
GSTM1 | ||||
All | 15 | Random (P < 0.001) | 1.17 (0.88–1.57) | 0.288 |
Ethnics | ||||
Caucasian | 9 | Random (P < 0.001) | 1.07 (0.753–1.53) | 0.712 |
Asian | 6 | Random (P < 0.001) | 1.37 (0.79–2.40) | 0.266 |
Study design | ||||
Population-based | 3 | Random (P = 0.001) | 1.17 (0.58–2.33) | 0.666 |
Hospital-based | 12 | Random (P < 0.001) | 1.18 (0.84–1.65) | 0.350 |
Gender | ||||
Male | 5 | Random (P = 0.035) | 0.89 (0.58–1.37) | 0.598 |
Female | 5 | Random (P < 0.001) | 1.02 (0.44–2.32) | 0.970 |
Subtype | ||||
Cortical | 4 | Random (P = 0.086) | 0.85 (0.59–1.23) | 0.386 |
Nuclear | 4 | Random (P = 0.084) | 0.97 (0.62–1.52) | 0.904 |
Posterior subcapsular | 3 | Fixed (P = 0.242) | 0.98 (0.72–1.32) | 0.879 |
Mixed | 4 | Random (P = 0.040) | 0.94 (0.60–1.48) | 0.792 |
GSTT1 | ||||
All | 9 | Random (P = 0.049) | 1.20 (0.96–1.51) | 0.105 |
Ethnics | ||||
Caucasian | 7 | Random (P = 0.058) | 1.11 (0.83–1.49) | 0.474 |
Asian | 2 | Fixed (P = 0.653) | 1.44 (1.14–1.83) | 0.003 |
Study design | ||||
Population-based | 2 | Fixed (P = 0.952) | 1.54 (1.16–2.05) | 0.003 |
Hospital-based | 7 | Random (P = 0.063) | 1.10 (0.84–1.45) | 0.498 |
Gender | ||||
Male | 5 | Fixed (P = 0.984) | 1.29 (0.98–1.70) | 0.073 |
Female | 5 | Fixed (P = 0.359) | 1.28 (0.97–1.69) | 0.078 |
Subtype | ||||
Cortical | 4 | Fixed (P = 0.186) | 1.09 (0.82–1.45) | 0.555 |
Nuclear | 4 | Random (P = 0.062) | 0.92 (0.52–1.62) | 0.774 |
Posterior subcapsular | 4 | Fixed (P = 0.219) | 1.42 (1.04–1.94) | 0.026 |
Mixed | 3 | Random (P = 0.097) | 1.21 (0.66–2.20) | 0.535 |