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Table 1 The enriched GO terms of differentially expressed genes

From: Screening of potential target genes for cataract by analyzing mRNA expression profile of mouse Hsf4-null lens

Term

Count

p-value

Genes

GO:0006974 ~ response to DNA damage stimulus

7

5.01E-05

SGK1, CRY2, REV1, TIMELESS, BTG2, DTL, HMOX1

GO:0051789 ~ response to protein stimulus

6

1.16E-04

FOS,EGR1, MSX1, HSPA4L, FAS, CYR61

GO:0001501 ~ skeletal system development

8

9.74E-04

PTGS2,ACVR2A, ALOX15, MSX1, UBC, COL1A1, BMPR1A, IDUA

GO:0010033 ~ response to organic substance

10

1.79E-03

FOS, EGR1,SGK1, MSX1, PYGM, HMOX1, HSPA4L, COL1A1, FAS, CYR61

GO:0009112 ~ nucleobase metabolic process

3

4.84E-03

UMPS, UOX, PPAT

GO:0006457 ~ protein folding

5

5.30E-03

HSPH1, HSPA4L, DNAJB1, DNAJB4, DNAJA4

GO:0033554 ~ cellular response to stress

8

6.81E-03

SGK1, CRY2, REV1, TIMELESS, BTG2, DTL, HMOX1, MAPK10

GO:0030509 ~ BMP signaling pathway

3

7.67E-03

ACVR2A, MSX1, BMPR1A

GO:0046456 ~ icosanoid biosynthetic process

3

9.65E-03

ALOX15, PTGS2, ALOX12

  1. GO gene ontology